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What is KPV?

Updated October 2026

KPV is a tiny three-amino-acid fragment of a much larger hormone — and that small size is exactly why researchers find it interesting.

What it is

KPV (lysine-proline-valine) is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (α-MSH). It reproduces the portion of α-MSH associated with anti-inflammatory signaling in research models, without the pigmentation activity of the full hormone.

Research directions

  • Inflammation-pathway signaling in cell culture
  • Epithelial and barrier-model research
  • NF-κB pathway studies

In blends

KPV is one of the four peptides in the "Klow" blend (with GHK-Cu, BPC-157, and TB-500). Supplied lyophilized for in-vitro research only.

Research-grade in the catalog