What is TB-500? A research overview
Updated October 2026
TB-500 is the research name for a synthetic peptide fragment of thymosin beta-4. It appears constantly in cell-migration literature — here's the actual science, laboratory-only.
What it is
TB-500 corresponds to the active region of thymosin beta-4 (Tβ4), a naturally occurring peptide involved in the regulation of actin, a key structural protein inside cells. The synthetic fragment reproduces the portion of Tβ4 responsible for actin binding, which is the property most studied in culture.
Research context
In-vitro and model research has examined TB-500 in connection with:
- Actin polymerization and cytoskeletal dynamics
- Cell migration in wound-closure assays
- Endothelial-cell behavior and angiogenesis models
Relationship to BPC-157
TB-500 and BPC-157 are frequently studied together — the combination is sold under the "Wolverine" blend name because both appear in overlapping tissue-repair research. They act through different mechanisms (actin regulation vs. angiogenic signaling), which is why researchers pair them.
Compliance
For in-vitro laboratory research only. Not for human or veterinary use. Each lot is third-party tested with a published COA.
Research-grade in the catalog